Research and practical guidance for APOE4 carriers
Understand APOE4.
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A new genetic result. Conflicting advice. A blood test you want to understand. Find clear explanations of APOE4 research, practical guides and questions to take to your doctor.
Written by Dr. Kevin TranDoctor of Pharmacy · APOE4/4 carrierStart with the free APOE4 guide Latest research
All articlesJust found out, or starting over?
Start with a clearer picture.
Understand what APOE4 means, then work through the basics of food, movement, sleep and supplements. The free Essential Guide brings them together in one place, with sources to explore and discuss with your doctor.
The questions that matter to you
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Explore what the research says about food, sleep, exercise, bloodwork and life with APOE4. Choose a topic, or search for the question you came with.
The APOE4 result that changed my life
The fear was real. So was the decision to act.
Dr. Kevin Tran6 min read
Your p-tau went up. Is your brain getting worse?
What a changed result does and doesn't mean. Plus Grant's tracker and your next expert question thread.
Dr. Kevin Tran9 min read
Brain fog: is it menopause, Alzheimer's or something else?
A neurologist explains the pattern she looks for, the limits of HRT research, and what she checks beyond symptoms.
Dr. Kevin Tran8 min readPhoenix Perks: up to 70% off blood tests, up to 35% off supplements
Blood tests and supplements at member prices, and why Phoenix keeps nothing on either
Dr. Kevin Tran8 min read
A failed trial just handed APOE4 carriers something more useful than a miracle
3,808 people. Two years. The biggest semaglutide trial for Alzheimer's came back negative. Before you write off GLP-1s, read this first.
Dr. Kevin Tran16 min read
Is low blood pressure starving your APOE4 brain?
Why symptoms matter, how to measure at home, and what the SPRINT findings do (and don't) show.
Dr. Kevin Tran9 min readHow to Lower ApoB for APOE4 Carriers
Lower ApoB for APOE4: your real targets, the diet and fiber levers that work, and the statin vs ezetimibe decision - all PubMed-cited, plain English.
Dr. Kevin Tran14 min readAPOE4 Supplements: What the Research Actually Supports
DHA, vitamin D, B-vitamins, curcumin: what the research really shows for APOE4 carriers, including where the evidence disagrees.
Dr. Kevin Tran18 min read
Is It Ever Too Late for HRT? Timing, Tests and What to Ask your Doctor
In this second part of my podcast with Steve Goldring, we discuss why it is not your birthday but your arteries, your bones, your numbers that actually decides whether HRT is for you.
Dr. Kevin Tran11 min readWritten by Dr. Kevin Tran, Doctor of Pharmacy
Free APOE4 guides.
Free guide
The Essential Guide to Thriving with APOE4
Beat the odds. Outsmart Alzheimer's.
Get the free guide
Free guide
The APOE4 Blood Work Blueprint
Evidence-based biomarker targets your doctor doesn't know about.
Get the free guide
Free guide
Genetic Playbook for Longevity & Brain Health
What to do with your raw DNA data—SNP by SNP.
Get the free guideWatch and listen
Go deeper into the questions.
Research explainers and conversations about the choices APOE4 carriers face, from bloodwork and brain health to everyday habits.
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The Blood Pressure Number That Cuts Dementia Risk | Dr. Jeremy Pruzin, MD
1:07:155.1K views
APOE4 and Menopause: Have You Missed the HRT Window? A Neurologist expert opinion.
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