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- We're securing early pharma access for ApoE4 carriers, and more! (join before pricing changes)
We're securing early pharma access for ApoE4 carriers, and more! (join before pricing changes)
The Phoenix in August: Patient Early Access Programs, subsidized Medtech devices, 80+ topics discussed
Hi Phoenix Friends,
In August, we crossed a critical threshold for our ApoE4 members.
We're now in active discussions with multiple pharma companies to secure early access to innovative therapies specifically for ApoE4 carriers—through clinical trials, early patient access programs, and other initiatives. When these programs launch, Phoenix members get cutting-edge therapies before they hit the market.
Time is of the essence.
The earlier we act, the better the results.
That's why leveraging our collective power is one of our core focus.
We're building two pathways to earlier interventions:
Early pharma access programs - First access to therapies with strong ApoE4 signals
Subsidized med-tech partnerships - We've secured heavily discounted pricing on medical devices in exchange for anonymized usage data and outcomes (cognition tests, blood markers, etc.). The medtech companies get real-world evidence. You get interventions at a fraction of the cost.
More partnerships details coming in the next newsletter once we finalize the details.
The Win-Win Structure We've Built:
Healthcare companies get real-world outcomes data, proof their solutions work, and patient advocacy.
You get interventions that could change your trajectory—earlier and cheaper than waiting years (or decades!) for general availability.
While we build these game-changing partnerships, our community is already delivering value every day.
In August alone, Phoenix members engaged in 80+ discussions on interventions, protocols, and strategies specific to ApoE4 carriers.
Carriers like you, sharing real results in real-time.
We are not a waiting room for future therapies: we are an active laboratory where members are testing, tracking, and sharing what works right now.
See the full list of topics at the end of this email.
This is your last call for Founding Member status.
Once we launch the Phoenix Experiment module (leveraging AI, big data, and digital twin technology to match you with interventions that work for people with your exact health profile), our pricing changes permanently.
The recurring costs of running these AI models force us to switch to a subscription model. There's no way around it.
Join now as a Founding Member: $499 one-time for LIFETIME access
Join after launch: $499 every year.
The door closes when the Phoenix Experiment module goes live.
Make your move.
If you have any questions, just reply to this email. I reply personally to each one of them.
P.S. The partner discounts we're negotiating could reimburse your lifetime membership with just one subsidized intervention. We're building a portfolio of these partnerships: blood tests, diagnostics, med-tech, pharma, and more.
The math is simple.
The decision should be too.
What you missed in The Phoenix Community in August
Quick summary of the most popular topics discussed this past month:
ALZ-801, vaccines, and lifestyle trials keep adding signal. This shapes real options you can act on.
Lipids stay center stage. Threads on ApoB, ezetimibe, DHA forms, rapamycin, and statins help you choose and track.
Fitness and sleep posts show clear wins. VO2 up, deep rest tools in play, and a new suvorexant discussion.
Biomarkers got practical. Ptau217 access and costs, direct-access menus by state, and real member data.
Genetics nuance grew. Protective variants and ancestry modifiers point to more precise plans.
All discussions by Space:
🧬 Research
Latest on ALZ-801 trial
Large POINTER study finds cognitive improvements with intensive structured lifestyle changes
We have to put this controversy to rest once and for all
AD clinical studiesWhat I learned from Rhonda Patrick’s analysis
APOE4: Scientists reversed memory loss + found social factors override genetics
APOE ε4 carriers share immune-related proteomic changes
New ApoE4 Science About Estrogen and Brain Health!
Reevaluating the role of education on cognitive decline
Vaccines and dementia Huge study showing benefits of two common vaccines, Shingles and RSV Varicose veins and dementia
ApoE4 & Alzheimer’s: 11 New Discoveries That Changed My Game Plan
ApoE4? New Brain Protection Breakthroughs Every Carrier Must See
(Small) study says intense lifestyle changes can not only stop but even reverse Alzheimer’sHandgrip study
💊 Supplements, Nutrition, and Medication
How to lower APOB
Interesting article from Peter Attia on inducing ketosis
Small human pilot study shows 20 g creatine supplementation improved brain energetics
Ezetimibe for prevention
What oil do you use for cooking?
Could Statins Be Our Secret Weapon Against Dementia?
Update on Lipids after 90 days on statin and ezetimibe
Online Source for peptides
These Omega-3s, they smell fishy…
Next Intervention – Rapamycin
Phospholipid-form DHA – what do you use?
Methylene Blue?
Choline (Alpha GPC), big “no regret” supplement
I Have Stopped Taking Ezetimibe
My view about keto: not adapted when doing 12h+ of sport per week
Has anyone used Saffron?
Microdosing Semiglutide
Nut Pods Y or N
Protein Bars
LPC-DHA (Lysoveta)
Dairy fat, Cheese, Cream.. Are they all equally bad for LDL-C?
Cholesterol medication?
Ursolic acid
Quality control on Supplement brands
Psyllium husk – For fiber and tactical use to blunt absorption
Is Alcohol good or bad for you? In moderation or not at all?
Anyone with experience with Kisunla (donanemad-azbt)?
Modified Citrus Pectin (MCP) and stress reduction
What do you do to keep lipids under control?
🏃 Sports, Sleep, and Stress Management
Suvorexant
Finally focusing on VO2 Max / Zone 4/5 Training
Sleep Optimization Sleep Trackers Research & More, Matthew Walker Interview
What sports / activities do you do?
Neuroplasticity Thread
Sleep optimization with mouth taping
Outsized effect interventions for brain clarity / avoiding brain fog
Factors affecting sleep – mystified
NSDR – Non Sleep Deep Rest
🔬 Biomarkers, Tracking, Monitoring
Lipoprotein(a) (Lp(a))
Cost of beta amyloid 40/42 and p-tau217 tests
Klotho may really help..
Obicetrapib – Delayed Progression p-Tau217
Any experience with Care Access screenings?
Direct-Access Testing by U.S. State
Cholesterol Balance Test Hyper absorb or Hyper produce
Anyone tried Dr Goodenowe’s ProdromeScan?
Increase in T-p-tau181
PET scan results indicate BAPL3, indicating substantial plaque build up
🧠 Mental Health & Emotional Resilience
You’re not alone — this space is for the emotional side of the journey
URGH! I’m overwhelmed and burnt out.
When I found out I had APOE4/4, my brain played tricks on me
💻 Tech and Medical Devices
Brain Health Dosing with Red Light Therapy
Red Light Therapy
Wearables
🧬 Genetics
My Genetics
3X4 Genetics – Memory and Brain Health Snps
Your Ancestry Changes How ApoE4 Works: 3 Breakthroughs
Deep dive into 3 protective APOE variants that block Alzheimer’s
📢 Announcements
Your Phoenix Monthly Check-In Just Got Smarter (And Way More Personal)
Shape the Ultimate Personalized APOE4 Protocol: Decide Which Features Matter to You!
🎁 Perks and Partnerships
Whole Genome Sequencing: Nucleus
Whole Genome Sequencing: Sequencing.com
Photo biomodulation: Neuronic
🤝 General and Off Topic
Opening address for Thurs July 31, 2025 at AAIC
AAIC presentation: The Importance of Early Detection
Alzheimer’s Association International Conference, Toronto, Canada
Blacked out 1 week of memory after taking meds for muscle / nerve injury
Labcorp vs Quest
Made a Decision on Kisunla Today
Long Term Care insurance – especially USA
Advanced Directive (More than Medical!)
Cure for Alzheimer’s?
If you’d like to join the discussion, apply to join the Phoenix Community here.
Onward,
Kevin