Hi Friends,

I can hardly believe we're already mid-October. This has been an extraordinary month—we've experienced explosive growth, secured crucial funding, and accelerated our mission to serve every APOE4 carrier who wants to take control of their brain health destiny.

Here's what happened while you were watching from the sidelines:

  1. Partnerships

  2. Release of our Phoenix App

  3. What happened inside the Phoenix Community

🤝 PARTNERSHIPS: Leveraging Our Collective Power

Successful Launch of Photobiomodulation Case Study with Neuronic

We kicked off an exclusive research partnership with Neuronic, giving our members first access to discover whether red light therapy could benefit their brain health. Cohort #1 enrollment closes October 21st (hard deadline: helmet received and study started by October 31st). This is the kind of cutting-edge opportunity that only becomes possible when we stand together.

Exclusive Access to Innovative Therapies

We're in advanced discussions with multiple healthcare companies to secure:

  • Early clinical trial enrollment for promising new treatments

  • Expanded patient access to innovative drugs before they hit the mainstream market

  • Bulk pricing discounts on interventions and biomarker testing

Some of these upcoming opportunities are particularly exciting because of their exceptional safety profiles and convenient delivery methods (pills, not infusions).

This is what happens when a community has real numbers.
We negotiate from strength.
We open doors that remain closed to individuals.
We turn "not available yet" into "available now."

📱 LAUNCH OF OUR NEW PHOENIX APP FOR APOE4 CARRIERS BY APOE4 CARRIERS

The future of personalized brain health optimization just got a major upgrade.
Our Phoenix App is now live, and it's already transforming how members track their protocols, stay updated on research, and connect with fellow APOE4 carriers who truly understand the journey.

Coming soon: AI-powered features that will analyze your biomarkers, suggest personalized interventions, and help you make sense of the overwhelming amount of research hitting the field every single day.

Supplements Tracker

  • Access the largest ApoE4-specific supplement library segmented by health benefits and strength of evidence

  • Find new supplements with efficacy and side effect stats

  • Find the best brands for each supplements

  • Manage daily adherence with calendar tracking

  • Get recommendation based on other members supplements stack that are similar to yours

Monthly and Daily Check-Ins

  • Comprehensive health assessments with 20+ metrics

  • Track your journey over time with trend analysis

  • Monitor symptoms, energy levels, and cognitive function

  • Build a detailed health timeline

Get access to these app today by applying to join the Phoenix Community!

IN DEVELOPMENT - Coming Soon

Blood Test Analysis & Phoenix Score

  • Upload PDFs, get AI-powered analysis in seconds

  • Track 100+ biomarkers with ApoE4-specific ranges

  • Receive your personalized "Phoenix Score"

  • Get actionable recommendations for optimization

  • Visualize trends and improvements over time

Interventions Dashboard ("My Stack")

  • Unified tracking for supplements, meds, and lifestyle

  • Daily adherence monitoring across all interventions

  • Smart reminders and streak tracking

  • Integration with blood test results

Attribution Wizard

  • AI-powered analysis to discover which interventions actually worked

  • Connect the dots between your actions and biomarker changes

  • Understand cause-and-effect in your health journey

  • Data-driven personalization

WHAT HAPPENED INSIDE THE PHOENIX COMMUNITY

Key Insights You Need to Know

The pace of breakthroughs is accelerating—and you don't want to miss what's coming next. September and October brought game-changing research that could fundamentally alter how we think about Alzheimer's prevention and treatment.

While mainstream media is still catching up, our community has already dissected these findings, shared practical applications, and connected the dots between cutting-edge science and daily actions.

Summary of discussions of most popular topics inside the Phoenix Community

Revolutionary research breakthroughs dominated: Stanford's complete memory restoration in AD models, experimental drugs clearing 50% of amyloid in hours, and new statistical models showing 43% of "failed" trial patients actually improved.

Blood biomarkers became more accessible: P-tau217 testing discussions, pre-FDA clearance options, and insights into tau scans disagreeing 47% of the time highlighted the complexity and promise of early detection.

Vaccine research gained momentum: Combined shingles and RSV vaccines showed over 30% AD risk reduction, with particularly strong effects in women.

Gut-brain connection emerged as a key theme: Fibrinogen's role in brain inflammation and how APOE4 carriers' unique gut bacteria impacts brain health sparked intense discussion.

Sleep, supplements, and lifestyle refinements continued: From Lysoveta dosing and nattokinase benefits to protein optimization, grounding practices, and fasting mimicking diets.

All discussion by topics below.

🚀 Ready to Stop Reading About It and Start Living It?

Every day you wait is another day of insights you're missing, connections you're not making, and optimizations you're not implementing.
The members who joined us months ago are now 10+ interventions ahead of where they started.
They're negotiating better testing prices.
They're enrolled in exclusive studies. They're part of something bigger than themselves.

🔥 Limited-Time Founding Member Offer

We're still accepting Founding Members—but this window is closing fast.

Right now, you can join The Phoenix Community with a lifetime membership as a Founding Member. This means you'll have permanent access to everything we build, including the AI-powered features we're about to release.

Once our AI features are fully implemented, we're transitioning to a yearly subscription model. When that happens, the Founding Member lifetime offer disappears forever.

Here's what you get as a Founding Member:

✅ Lifetime access to the Phoenix Community (no recurring fees, ever)
✅ Access to our new Phoenix App with upcoming AI features
✅ Exclusive research study opportunities (like our Neuronic partnership)
✅ Priority access to early clinical trials and innovative therapies
✅ Bulk pricing discounts negotiated through our collective buying power
✅ Direct connection with thousands of APOE4 carriers, researchers, and clinicians
✅ Real-time research translation (not 18-36 months later)

This is your moment. The AI features are coming. The pricing model is changing. The Founding Member window is closing.

Join The Phoenix Community as a Founding Member →

Don't let another month go by while breakthrough research passes you by.

Let’s beat the odds,
Kevin

P.S. — Still on the fence? Consider this: Every person who joined our community three months ago now has access to interventions, studies, and insights that won't reach mainstream medicine until 2026 or later.
What could six months of optimized protocols be worth to your future self?

All discussions by topic

📢 Announcements

  • Launch of our new Phoenix App

  • We're a GO on Neuronic Study + Sep Monthly check ins / Oct Pods

🎁 Perks and Partnerships

  • Neuronic study - Cohort 1

  • Partnering with Alzheon (Valiltramiprosate)

  • Join our research study: 1070nm Photobiomodulation with Neuronic and get your subsidized device

  • Untitled post (Wendy Rowan, Oct 3)

🧬 Research

Breakthrough Studies & Clinical Trials:

  • Stanford achieves COMPLETE memory restoration in AD models by blocking metabolic switch + 75% patients have hidden sleep apnea (and it's consequences!)

  • Experimental drug clears 50% of amyloid from AD mouse brains in two hours with a single dose

  • Revolutionary Statistical Models Reveal 43% of "Failed" Alzheimer's Trial Patients Actually Improved

  • Simple Blood Test Detects Alzheimer's 15-20 Years Before Symptoms (P-tau217 + Other New Biomarkers)

  • Conference Analysis: Two FDA-approved tau scans disagree 47% of the time, one detects 3-5 years earlier

  • 3 Hidden Mechanisms of Tau-Driven Neurodegeneration revealed by Cambridge scientists

APOE4-Specific Research:

  • Rapamycin for APOE4

  • Some Apoe4 color and research I received from Dr. Greicius at Stanford earlier this year

  • Cognitive reserve protects mood/behavior, not just memory + Insights on how to build your own cognitive reserve no matter your age

  • Your Gut Bacteria Controls Your Brain (and Why APOE4 Carriers Stand Apart)

  • APOE4/4 in the news - what would scientists do?

Vaccine & Prevention Research:

  • Vaccine for shingles and rsv shown to reduce Ad risk by over 30% in combination (20% if only taking shingles vaccine) Stronger effect in women

Protein & Biomarker Research:

  • 97% of blood-induced brain inflammation comes from ONE protein (fibrinogen)

  • A protein in the brain called KIBRA may be able to rescue later stage disease

  • Plasma p-Tau can be driven by factors other than abnormal amyloid levels

Diet & Lifestyle Research:

  • Mediteranian diet reduces AD risk especially in apoe4 carriers, highest effect in homozygots (more than 35%)

  • 100 grams protein a day, but low fat? How?

General Research:

  • Interesting summary and graphics from Scientific American on the 138 ALZ drugs currently under clinical trials

  • Interesting talk and AD hypothesis

  • Very interesting article research on Alzheimer's genetics

  • Interesting NeuroAge therapeutics studies biomarkers, genetics and creates a drug with AI specifically for you

  • Dr. Bruce Yankner interviewed regarding lithium research by Katie Couric

  • Peter Attia summary of Lithium research

  • Digital twins and virtual experiments

  • Mind Crowd Study! Pass it along!

  • Huntington's Breakthrough

  • Lessons from living until 117

  • WEB STUDY: Webinar/Biomarkers

  • USC new funding

  • News out of Stanford:Rethinking Alzheimer's

  • Biometric scan

  • DMSO for Alzheimer's/ Dementia Article

  • Statin benefits for AD for APOE4/4 carriers?

  • Do we need a section for AD Trials & exclusion factors

💊 Supplements, Nutrition, and Medication

Omega-3 & Phospholipids:

  • Lysoveta optimal dosing

Supplements:

  • Huperzine A - Anyone Taking?

  • Anyone supplementing with Creatine?

  • Nattokinase: A Natural Ally for Brain Health in APOE4 Carriers

Nutrition & Diet:

  • Exogenous Ketones for brain fog and energy crashes

  • Anyone else done Prolon's Fasting Mimicking diet?

  • Let me share a little about me as I cross post here with the biomarkers post

  • Common Cold

Medications:

  • Bristol Myers Squibb's Anti-MTBR-Tau-Targeting Antibody, BMS-986446, Granted Fast Track Designation by U.S. FDA for the Treatment of Alzheimer's Disease

  • Statin causing me to overabsorb now?

Supplement Sourcing:

  • 30% discount offering on supplements

  • Favorite Krill Oil?

🏃 Sports, Sleep, and Stress Management

  • Calculate heart rate zones?

  • Thoughts on Grounding/Earthing?

🔬 Biomarkers, Tracking, Monitoring

  • Anyone get any Brain Key reports?

  • Let me share a little about me

  • Free cholesterol test

  • Plasma p-Tau can be driven by factors other than abnormal amyloid levels

  • Pre FDA clearance tau-related blood test

  • Quest p-tau217 plasma result

  • Got my Boston Heart results. Who can help decipher this?

  • I found cheaper cholesterol testing!

💻 Tech and Medical Devices

  • Neuronic Experiences

  • Using AI as a health coach - huge success and some tips!

🧬 Genetics

  • Apoe4 Subset: Exploring Distinct Familial Trajectory

  • Anyone who's done sequencing.com that can help me with a question?

  • Any experience with TellmeGen WGS?

  • Dr. Ben Lynch - Dirty Genes

  • 23andMe Total Health vs Bredesen's Apollo

💝 Mental Health & Emotional Resilience

  • Considering lower face and neck lift for 54th bday present to myself. Having apoe 4 4, makes me totally want to keep looking young.

  • Update since "feeling sad" post

  • Feeling sad...

🤝 General and Off Topic

  • ketone urine strips - have you found any to be accurate?

  • Fragilized teeth due to supplements?

  • South Africa and Israel

  • How to find a MD ally?

  • Personality test very on point :)

🔬 Experiments and Open Journal

  • My N=1 Movement Experiment

If you'd like to join the discussion, apply to join the Phoenix Community here.

Onward,

Kevin

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